Diverging slightly from a career in restaurants and foodservice, Daniel Westiner has created his own small-batch commercial roasting operation, Other Animal Coffee Roasters, in South Philadelphia’s Point Breeze neighborhood. The roastery concept has been developing in Westiner’s mind for a period of years, forming in earnest after Westiner managed the opening of Talula’s Daily, an upscale, food-focused cafe concept spun off from the farm-to-table […]
STUDY QUESTION: Is caffeine and caffeinated beverage consumption associated with the risk of spontaneous abortion (SAB)?
SUMMARY ANSWER: While preconceptional caffeine consumption was not materially associated with an increased risk of SAB, consumption during early pregnancy was associated with a small increased risk of SAB, although the relation was not linear.
WHAT IS KNOWN ALREADY: Caffeine has been hypothesized as a risk factor for SAB since the 1980s; however, results from previous studies have been conflicting.
STUDY DESIGN, SIZE, DURATION: This prospective cohort study included 5132 Danish women planning pregnancy and enrolled from 2007 to 2010.
PARTICIPANTS/MATERIALS, SETTING, METHODS: Participants were women who conceived after entry into the Snart-Gravid cohort and who were aged 18-40, in a stable relationship with a male partner, and did not use fertility treatments to conceive. Women reported their daily caffeine and caffeinated beverage consumption on questionnaires before conception and during early pregnancy. All exposure measurements were prospective with respect to outcome ascertainment. We estimated hazard ratios (HRs) of SAB for categories of caffeine consumption in milligrams (mg) per day and the corresponding 95% confidence intervals (CIs) using Cox proportional hazards regression models with gestational weeks as the time scale.
MAIN RESULTS AND THE ROLE OF CHANCE: There were 732 women (14.3%) who were identified as having a SAB. In the preconceptional period, caffeine consumption was not materially associated with SAB risk (HR comparing ≥300 with <100 mg/day: 1.09; 95% CI: 0.89, 1.33). In early pregnancy, the HRs for 100-199, 200-299 and ≥300 mg/day of caffeine consumption were 1.62 (95% CI: 1.19, 2.22), 1.48 (95% CI: 1.03, 2.13) and 1.23 (95% CI: 0.61, 2.46), respectively, compared with that for <100 mg/day.
LIMITATIONS, REASONS FOR CAUTION: The observed results may be affected by non-differential exposure misclassification, reverse causation and residual confounding.
WIDER IMPLICATIONS OF THE FINDINGS: This is the largest study to date of prospectively measured, preconception caffeine consumption and risk of SAB. We were able to reduce the likelihood of differential left truncation bias and recall bias present in other analyses.
The post K A Hahn et al, 2015. Caffeine and Caffeinated Beverage Consumption and Risk of Spontaneous Abortion, Human Reproduction, published online ahead of print. appeared first on Coffee and Health.
San Francisco-based Philz Coffee has secured $15 million in investments from sources including Jonah Hill and Snoop Dogg, with plans to expand its retail footprint nationwide. News site Techcrunch, whose founder Michael Arrington founded a company representing one of the angel investors, broke the story early today, reporting that the Series B round of financing was led by the investment firm Summit Partners, the […]
Following the recent opening of its first Los Angeles bar, and fourth total, Santa Cruz-based Verve Coffee Roasters has plans to open at least four more L.A. neighborhood shops. “Los Angeles has always been at the forefront of our minds when we thought about expansion beyond Santa Cruz because of its diverse and neighborhood-centric culture,” Verve Co-founder Colby Barr said in an announcement […]
Obesity affects 18% of U.S. children. In a recent report, maternal consumption of ≥150 mg of caffeine per day during pregnancy was associated with increased odds for obesity in the offspring (odds ratio = 2.1 [95% confidence interval = 1.2-3.5]). If this association was causal, a considerable fraction of childhood obesity might be prevented by reduction of caffeine intake in pregnancy.
We studied 1986 mother-child pairs who were controls from a case-control study of caffeine metabolites and spontaneous abortion nested within the Collaborative Perinatal Project. Women were pregnant during 1959-1966, and children were followed with visits at 48 and/or 84 months of age, when height and weight were measured according to a standardized protocol. Serum was drawn at <20 and ≥26 weeks’ gestation and assayed for paraxanthine (caffeine‘s primary metabolite) by high-performance liquid chromatography. Relative risks of obesity (body mass index ≥95th percentile for age and sex) were estimated by log-binomial or Poisson regression and adjusted for maternal age, race, education, smoking, prepregnant weight, diabetes in pregnancy, and gestational age at blood draw.
Obesity prevalence was 11.7% at 48 months and 6.5% at 84 months. Associations of maternal serum paraxanthine and child obesity were nonlinear, and adjustment reduced the magnitude of all associations. The maximum relative risk (approximately 1.4) was for the association of paraxanthine drawn at <20 weeks with obesity at ages 48 and 84 months.
This study does not support an increased risk of childhood obesity with increasing maternal caffeine consumption during pregnancy.
The post M A Klebanoff and S A Keim, 2015, Maternal serum paraxanthine during pregnancy and offspring body mass index at ages 4 and 7 years, Epidemiology, Volume 26 (2): 185-191, online ahead of print. appeared first on Coffee and Health.
Introduction: Specific coffee subtypes and tea may impact risk of pre- and post-menopausal breast cancer differently. We investigated the association between coffee (total, caffeinated, decaffeinated) and tea intake and risk of breast cancer.
Methods: A total of 335,060 women participating in the European Prospective Investigation into Nutrition and Cancer (EPIC) Study, completed a dietary questionnaire from 1992 to 2000, and were followed-up until 2010 for incidence of breast cancer. Hazard ratios (HR) of breast cancer by country-specific, as well as cohort-wide categories of beverage intake were estimated.
Results: During an average follow-up of 11 years, 1064 premenopausal, and 9134 postmenopausal breast cancers were diagnosed. Caffeinated coffee intake was associated with lower risk of postmenopausal breast cancer: adjusted HR¿=¿0.90, 95% confidence interval (CI): 0.82 to 0.98, for high versus low consumption; P trend = 0.029. While there was no significant effect modification by hormone receptor status (P = 0.711), linear trend for lower risk of breast cancer with increasing caffeinated coffee intake was clearest for estrogen and progesterone receptor negative (ER-PR-), postmenopausal breast cancer (P = 0.008). For every 100 ml increase in caffeinated coffee intake, the risk of ER-PR- breast cancer was lower by 4% (adjusted HR: 0.96, 95% CI: 0.93 to 1.00). Non-consumers of decaffeinated coffee had lower risk of postmenopausal breast cancer (adjusted HR = 0.89; 95% CI: 0.80 to 0.99) compared to low consumers, without evidence of dose-response relationship (P trend = 0.128). Exclusive decaffeinated coffee consumption was not related to postmenopausal breast cancer risk, compared to any decaffeinated-low caffeinated intake (adjusted HR = 0.97; 95% CI: 0.82 to 1.14), or to no intake of any coffee (HR: 0.96; 95%: 0.82 to 1.14). Caffeinated and decaffeinated coffee were not associated with premenopausal breast cancer. Tea intake was neither associated with pre- nor post-menopausal breast cancer.
Conclusions: Higher caffeinated coffee intake may be associated with lower risk of postmenopausal breast cancer. Decaffeinated coffee intake does not seem to be associated with breast cancer.
The post N Bhoo-Pathy et al, 2015, Coffee and tea consumption and risk of pre- and postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study, Breast Cancer Research, Volume 17, published online ahead of print. appeared first on Coffee and Health.
Mazarine Coffee, a beautifully designed new multiroaster coffee bar with many of the accoutrements du jour opened last month in downtown San Francisco, on Market Street between Geary and O’Farrell. Named after the oldest library in Paris, Mazarine is the ambitious debut coffee project of native Iranian Hamid Rafati, who moved to the Bay Area in 1997 to study engineering at UC Berkeley and […]
Background: Epidemiological studies that have investigated the association between coffee, tea and caffeine consumption and ovarian cancer risk have produced conflicting results. Furthermore, only few studies have examined the role of coffee and tea consumption separately for borderline ovarian tumors. By use of data from a large Danish population based case-control study, we examined the risk of ovarian tumors associated with coffee, tea, and caffeine consumption with a particular focus on characterizing risks by tumor behavior and histology.
Material and methods: From 1995 through 1999, we included 267 women with ovarian cancer, 115 women with borderline ovarian tumors and 911 randomly selected control women. All women completed a beverage frequency questionnaire with detailed information on coffee and tea consumption. Analyses were performed using multiple logistic regression models.
Results: Both coffee (OR 0.90; 95% CI 0.84 – 0.97 per cup/day) and total caffeine consumption from coffee and tea combined (OR 0.93; 95% CI 0.88 – 0.98 per 100 mg/day) decreased the risk of ovarian cancer. These associations were significant only for the serous and “ other ” subtypes of ovarian cancer. No relation between tea consumption and ovarian cancer risk was observed. The risk estimates for borderline ovarian tumors resembled those observed for ovarian cancer, but did not reach statistical significance.
Conclusions: Our results indicate that coffee consumption and total caffeine consumption from coffee and tea combined is associated with a modest decreased risk of ovarian cancer. However, more biological studies are needed to identify bioactive chemical compounds in coffee that potentially could affect ovarian cancer development.
The post C F Gosvig et al, 2015. Coffee, tea, and caffeine consumption and risk of epithelial ovarian cancer and borderline ovarian tumors: Results from a Danish case-control study, Acta Oncol, published online ahead of print. appeared first on Coffee and Health.
On January 9, venerable Sacramento roaster/retailer Temple Coffee tweeted about a “controversial cupping.” One of our more interesting, and definitely most controversial public cupping will take place today at 2pm. 2829 S street, free to all. — Temple Coffee (@templecoffee) January 9, 2015 “Controversial cupping” is not a phrase you hear every day: @templecoffee Controversial? Pray, tell. — Daily Coffee […]
OBJECTIVE: To evaluate the effect of caffeine on balance control of hemiparetic stroke patients, we investigated the difference in postural stability before and after drinking coffee by observing changes in stability index (SI) from posturography.
METHODS: Thirty patients with history of stroke and 15 age-matched healthy subjects participated in this study. Effect of group factor (of the control and stroke groups) and treatment factor (pre- and post-drinking of coffee) on SI were tested in three conditions: with eyes opened, with eyes closed, and with a pillow support. The effects of these factors on visual deprivation and somatosensory change of subjects were also tested.
RESULTS: Under all conditions, SI was higher in the stroke group than in the control group. Under eyes-open condition, the treatment factor was not statistically significant. Under eyes-closed condition, the interaction between group and treatment factor was statistically significant. After the subjects drank coffee, SI in the control group was increased. However, SI in the stroke group was decreased. Under pillow-supported condition, the interaction between group and treatment factor appeared marginally significant. For visual deprivation effect, the interaction between treatment and group factor was statistically significant. After caffeine consumption, the visual deprivation effect was increased in control group but decreased in the stroke group. For somatosensory change effect, the interaction between group and treatment factor was not statistically significant.
CONCLUSION: Postural stability of hemiparetic stroke patients related to somatosensory information was improved after intake of usual dose of caffeine.
The post W S Kim et al, 2014, Usual dose of caffeine has a positive effect on somatosensory related postural stability in hemiparetic stroke patients, Annals of Rehabilitation Medicine, published online ahead of print. appeared first on Coffee and Health.